Aceclofenac
Indications
Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and lumbago.
Pharmacology
Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.
Dosage & Administration
Extended release tablet: The recommended dose in adults is one 200 mg Aceclofenac tablet daily or as prescribed by the physician.
Film coated tablet: The recommended dose in adults is 100 mg, twice daily.
Drug Interactions
No significant drug interactions has not been observed but close monitoring of patients is required when it is used with:
- Lithium and Digoxin: may increase plasma concentration of lithium and digoxin.
- Diuretics: may interact the activity of diuretics.
- Anticoagulants: may enhance the activity of anticoagulant.
- Methotrexate: may increase the plasma level of methotrexate.
Contraindications
Aceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.
Side Effects
Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.
Pregnancy & Lactation
The use of Aceclofenac should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
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Precautions & Warnings
Caution should be exercised to patients with active or suspected peptic ulcer or gastro-intestinal bleeding moderate to severe hepatic impairment and cardiac or renal impairment. Caution should also be exercised in patients suffering from dizziness or urticaria.
Therapeutic Class
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Special Populations
There are no clinical data on the use of Aceclofenac in children.
Storage Conditions
Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and lumbago.
A-Pak
AC PR
Acebid
Aceclof
Aceclofen
Aceclora
Acecol
Acedol
Acedol
Acedol SR
Acedol SR
Acefenac
Acefenac
Acegic
Acegic
Acelock
Acelock
Acelon
Acenac
Acenopan
Acepro
ACF
Acflam
Aclo
Aclonac
Aclovix
ACN
Alcefen
Alofen
Alona
Analgen
Apeclo
Apeclo SR
Apitac
Avenac
Biofenac
Casyn
Ceclofen
Ceclonac
Celofen
Claim
Claim ER
Clof
Dolonac
Dolonac
Ecena
Ectinac
Ena
Exipain
Ezemove
Fenacin
Fixonac
Fleco
Flexi
Flexi SR
Flexidol
Flexivan
Flexivan ER
Freemax
Grofenac
Hifenac
Intas
Labenac
Labenac SR
Lofam
Lofens
Maxpain
Mervan
Mervan SR
Motifen
Movex
Movex SR
Movon
Movon
Noak
Nofenac
Nostrin
Orcenac
Orifen
Ostoflex
Painex
Painkil
Paino
Penac-AC
Polynac
Ponos
Preservin
Preservin SR
Protilez
Qrip
Relise
Remave SR
Repidor
Reservix
Reservix SR
Rheuma
Rheuma
Rheuma
Ruclon
Sapclo
SB-Acelo
SB-Acelo
Servex
Silfenac
Silfenac
Technofen
Tek
Ternilla
Vaxtin
Volfenac
Xa Fast
Xerifen
Xerifen
Xerifen
Xtrafen
Xtrafen SR
Xtrafen SR
Zerodol
Zolfin
Zolonac